Author: John Green
Published: March 18, 2025, by Crash Course Books
Format: Hardcover, 198 Pages
Genre: Non-Fiction
Blurb: Tuberculosis has been entwined with humanity for millennia. Once romanticized as a malady of poets, today tuberculosis is seen as a disease of poverty that walks the trails of injustice and inequity we blazed for it.
In 2019, author John Green met Henry Reider, a young tuberculosis patient at Lakka Government Hospital in Sierra Leone. John became fast friends with Henry, a boy with spindly legs and a big, goofy smile. In the years since that first visit to Lakka, Green has become a vocal advocate for increased access to treatment and wider awareness of the healthcare inequities that allow this curable, preventable infectious disease to also be the deadliest, killing over a million people every year.
In Everything Is Tuberculosis, John tells Henry’s story, woven through with the scientific and social histories of how tuberculosis has shaped our world—and how our choices will shape the future of tuberculosis.
My Opinion: I can’t be the only one who didn’t realize that John Green—yes, the John Green of The Fault in Our Stars and Looking for Alaska—also writes nonfiction. This novel was a surprise on that front alone, but the real surprise was how much I didn’t know about a disease I assumed belonged to history.
Everyone has heard of tuberculosis, but far fewer understand the political machinery, global inequities, and maddening contradictions that surround it. Green points out more than once that the countries with the highest burden of TB often don’t have access to the cure, while the countries that do have the cure rarely see the disease anymore. It’s a bleak little paradox that sets the tone for the rest of the book.
As I kept reading, I began to feel that Green wasn’t trying to give readers a complete education so much as he was nudging us toward our own deeper research. And it worked. I wandered down more than a few rabbit trails before reminding myself to return to what he wanted me to see: tuberculosis is, at its core, a disease of injustice.
One idea kept circling back to me. Centuries from now, readers will look at our 2026 medical practices with the same disbelief we feel when reading about treatments from the past. It’s humbling, and more than a little uncomfortable.
There is repetition in this book, but it’s purposeful. Green keeps pressing on the same truths: cost effectiveness should never determine who gets to live; pharmaceutical companies are driven by profit; and while TB can strike anyone, it is the poor—those without clean water, reliable food, or access to treatment—who bear the heaviest burden. When the world decides which lives are “worth” saving, the same people are always left behind.
The book is an easy read in terms of prose, but not a fast one, and certainly not a light one. The footnotes alone can send you off in ten different directions, and you’ll likely finish with more questions than answers. One question lingered for me: tuberculosis is notoriously good at evolving into drug resistant forms. So, what does the future look like when there have been no new TB drugs in forty years? That’s a long time for a microbe to invent new tricks.
Green doesn’t pretend to have all the answers, but he does make sure you understand the stakes. And once you do, it’s hard to stop thinking about them.
In 2019, author John Green met Henry Reider, a young tuberculosis patient at Lakka Government Hospital in Sierra Leone. John became fast friends with Henry, a boy with spindly legs and a big, goofy smile. In the years since that first visit to Lakka, Green has become a vocal advocate for increased access to treatment and wider awareness of the healthcare inequities that allow this curable, preventable infectious disease to also be the deadliest, killing over a million people every year.
In Everything Is Tuberculosis, John tells Henry’s story, woven through with the scientific and social histories of how tuberculosis has shaped our world—and how our choices will shape the future of tuberculosis.
My Opinion: I can’t be the only one who didn’t realize that John Green—yes, the John Green of The Fault in Our Stars and Looking for Alaska—also writes nonfiction. This novel was a surprise on that front alone, but the real surprise was how much I didn’t know about a disease I assumed belonged to history.
Everyone has heard of tuberculosis, but far fewer understand the political machinery, global inequities, and maddening contradictions that surround it. Green points out more than once that the countries with the highest burden of TB often don’t have access to the cure, while the countries that do have the cure rarely see the disease anymore. It’s a bleak little paradox that sets the tone for the rest of the book.
As I kept reading, I began to feel that Green wasn’t trying to give readers a complete education so much as he was nudging us toward our own deeper research. And it worked. I wandered down more than a few rabbit trails before reminding myself to return to what he wanted me to see: tuberculosis is, at its core, a disease of injustice.
One idea kept circling back to me. Centuries from now, readers will look at our 2026 medical practices with the same disbelief we feel when reading about treatments from the past. It’s humbling, and more than a little uncomfortable.
There is repetition in this book, but it’s purposeful. Green keeps pressing on the same truths: cost effectiveness should never determine who gets to live; pharmaceutical companies are driven by profit; and while TB can strike anyone, it is the poor—those without clean water, reliable food, or access to treatment—who bear the heaviest burden. When the world decides which lives are “worth” saving, the same people are always left behind.
The book is an easy read in terms of prose, but not a fast one, and certainly not a light one. The footnotes alone can send you off in ten different directions, and you’ll likely finish with more questions than answers. One question lingered for me: tuberculosis is notoriously good at evolving into drug resistant forms. So, what does the future look like when there have been no new TB drugs in forty years? That’s a long time for a microbe to invent new tricks.
Green doesn’t pretend to have all the answers, but he does make sure you understand the stakes. And once you do, it’s hard to stop thinking about them.